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CNN —The grieving parents of two Australian brothers killed on a surfing trip in Mexico alongside their American friend said their deaths had made the world a “darker place,” days after their sons’ bodies were identified. On Sunday, Mexican authorities confirmed their identities as the three missing friends with the help of relatives who flew out help investigators. Mexican authorities have vowed to investigate the murders, saying the surfers may have been attacked in an attempted vehicle robbery. Mexico’s homicide rate is among the highest in the world, and more than 100,000 people remain missing in the country. Studies show only around seven percent of murders in Mexico are ever solved.
Persons: Jake, Callum Robinson, Jack Carter Rhoad, , Debra Robinson, , Carter Rhoad, Martin, Callum, “ Callum, Debra, Callum’s, Penny Wong, Jesús Gerardo “, “ El Organizations: CNN, Seven Network Australia, Australia’s, team, Seven, Department of Foreign Affairs, Trade, Australian Federal Police, Australian Embassy Locations: Mexico, Ensenada, Tijuana, San Diego, Perth, Australia, United States, Baja California
An analogy for understanding the development of AI drugs can be found in the mechanisms of ChatGPT. As a result, it's a drug discovery process that has a 90% failure rate. Some of the noted flaws of generative AI, its propensity to "hallucinate" for example, could prove to be powerful in drug discovery. AI is learning to distinguish drugs from non-drugs, and to create new drugs, in the same way that ChatGPT can create sentences, Ellington said. Now, AI models are helping narrow down the possibilities, so scientists more quickly know the optimal modifications to try.
Persons: ChatGPT, Kimberly Powell, Google's, , AlphaFold, Powell, Rau, Lilly, Eli Lilly, Diogo Rau, It's, Amgen, Andy Ellington, Ellington, Daniel Diaz, Diaz, We've Organizations: Nvidia, CNBC Technology, Summit, University of Texas, Austin, NVIDIA, biosciences, UT's Institute, Foundations of Machine, Cadence Locations: Nature
The Food and Drug Administration on Wednesday approved the sale of an antibiotic for the treatment of urinary tract infections in women, giving U.S. health providers a powerful new tool to combat a common infection that is increasingly unresponsive to the existing suite of antimicrobial drugs. The drug will be marketed in the U.S. as Pivya and will be made available by prescription to women 18 and older. It is the first time in two decades that the F.D.A. has approved a new antibiotic for U.T.I.s, which annually affect 30 million Americans. is committed to fostering new antibiotic availability when they prove to be safe and effective.”
Persons: U.T.I.s, Dr, Peter Kim Organizations: Drug Administration, Drug, Research Locations: Europe, U.S
CNN —It’s 420 or “weed day,” and people around the world will be paying homage to their favorite guilty pleasure: marijuana. “I worry when people are in an enclosed space because new data is beginning to show that secondhand marijuana smoke may be just as dangerous as the primary smoke,” Page said. “Approximately 3 in 10 people who use marijuana have marijuana use disorder,” according to the US Centers for Disease Control and Prevention. In fact, some parents told doctors they believed vaping marijuana was safer than tobacco, Boyd told CNN earlier via email. A cloud of marijuana smoke rises as a clock hits 4:20 p.m. during the Mile High 420 Festival in Denver on "weed day" in 2022.
Persons: CNN —, Dr, Beth Cohen, Cohen, , , Robert Page II, ” Page, Weed, It’s, ’ ” Carol Boyd, Ann Arbor, Peter Grinspoon, ” Young, Sam Wang, Boyd, Grinspoon, Patrick T, Fallon, Nixon, ” Boyd, ” Grinspoon, ’ ”, Page Organizations: CNN, District of Columbia, University of California, University of Colorado Skaggs School of Pharmacy, Pharmaceutical Sciences, Center, Drugs, University of Michigan, US Centers for Disease Control, Prevention, CDC, Massachusetts General Hospital, Marijuana, Children’s Hospital, Yale Medicine, Drug, University of Colorado’s, Getty, University of Mississippi, US Drug, Administration Locations: United States, San Francisco, Colorado, Aurora, Ann, Boston, Children’s Hospital Colorado, Denver, AFP
Veteran treatment courts, which prioritize rehabilitation for convicted veterans, provide comprehensive care, but the public version of these courts fail to deliver comparable support. Landing in a treatment courtAs of 2022, there were over 4,153 adult drug courts and 511 veteran treatment courts in the United States. There are numerous ways a person who has been convicted can enter a drug treatment court. Many adult drug treatment courts are unable to admit violent offenders due to the BJA prohibition. He describes his veteran treatment court experience as going through an "intense supervised probation" that gradually lessened.
Persons: , Christopher Deutsch, Deutsch, there's, Christina Lanier, John Pendygraft, Pool Lanier, they're, Lanier, Ed Kubo, Michael Peacock, Kristen Wong Deutsch, Hondo Underwood, Underwood, BI's Ju Shardlow, Jack Milton Organizations: Service, Business, Court, Center, Criminal, AP, UNC Wilmington, Army, Treatment, Supreme Court, Marine Corps, Justice, Harbor, Veterans Affairs, Portland Press, Getty Locations: Clearwater , Florida, Raleigh, North Carolina's, Wilmington, United States, Hawaii, Colorado
Nuvalent could be a winning biotech in the world of cancer treatments, according to Jefferies. Analyst Roger Song initiated the clinical-stage biopharmaceutical company with a buy rating and $97 price target, which implies 49.8% potential upside for shares over the next 12 months. "NUVL leverages strong expertise in structure-based chemistry and deep understanding of unmet [patient] needs to develop potentially 'best-in-class' small molecule targeted cancer therapy," Song wrote in a Wednesday note. "We think both candidates poise well in later line and have strong potential to move into frontline treatments." The company posted a fourth-quarter loss that was slightly wider than expected, at 62 cents per share.
Persons: Roger Song, Jefferies Organizations: Jefferies, U.S . Food, Drug Administration, FactSet Locations: U.S
Read previewAustin Walters started SpringTide Ventures in 2018 to disrupt healthcare by democratizing access to health innovations. The firm just closed its second $65 million fund to make more of those bets. A tough fundraising environmentAfter closing on its first $20 million fund, which the firm began investing out of in 2019, SpringTide originally set a $100 million target in 2021 for its second fund, Walters said. SpringTide picks a different focus area each time — most recently, home health, where the firm has invested in companies like family primary care startup Nest Health. By solving significant problems with advanced technologies, these companies have natural competitive advantages that allow them to drive outsize returns for the firm, Walters said.
Persons: , Austin Walters, Walters, Henry Ford, We're, SpringTide, Justin Hackworth Photgraphy SpringTide, OpenLoop, outsize, SpringTidew hasn't, " Walters Organizations: Service, SpringTide Ventures, Tiger Global, Sonic Healthcare, Business, Health, Ally Bank, Troomi Wireless Locations: Boston, San Francisco, Salt Lake City, New York
British techbio startup Qureight has secured $8.5 million in an oversubscribed Series A round. Launched in 2018, Qureight wants to simplify how pharma companies deal with the complex datasets often used during clinical trials. "For example, we can start to structure images of lungs using AI," said cofounder and CEO Muhunthan Thillai. The startup primarily works with pharmaceutical companies, including heavyweights such as AstraZeneca, as well as hospitals and clinical research organizations. Check out the 11-slide pitch deck used to secure the fresh funding.
Persons: Qureight, Muhunthan Thillai, Thillai, Hargreave Hale Organizations: pharma, Business, AstraZeneca, Hargreave Hale AIM VCT, XTX Ventures, Guinness Ventures, Playfair, Fund, Cambridge Angels Locations: Cambridge, Meltwind
While other dogs also played similar roles and were paraded for the media, Roger captured the island’s imagination — partly because of his backstory of an initial career failure. But his ebullient personality and intelligence made him a much better candidate to be a rescue dog, which was the career that was then chosen for him. Kaohsiung Fire DepartmentChen Chih-san, captain of the rescue dog unit of the Kaohsiung Fire Department, told reporters that Roger was transferred to the rescue training school when he was 1 year old. According to the Kaohsiung City Government, Roger was certified by the International Rescue Dog Organization in 2022, an accolade last achieved by a Taiwanese rescue dog in 2019. But retirement is looming for Roger, with the Kaohsiung Fire Department sending rescue dogs to a suitable home once they reach age 9, CNA said, citing Chen.
Persons: Roger, Kaohsiung Fire Department Roger, Chen Chih, “ I’m, ” Chen, ” Roger, Chen Organizations: Taiwan CNN, Central News Agency, CNA, Kaohsiung Fire Department, Kaohsiung Fire, Kaohsiung City Government, Dog Organization Locations: Taipei, Taiwan, lunged, Kaohsiung
The Denver-Boulder region is rapidly emerging as a major hub for the life sciences industry, attracting companies that develop cutting-edge medical treatments and technologies. Life sciences research aims to understand living things, from cells to our planet, to improve health, food and the environment. Founded in 2003, the Bioscience Association supports the growth of life sciences, with a focus on access to capital, education, networking and more. A recent CBRE report found Denver-Boulder to be the top U.S. life sciences real estate market, fueled by record investment from venture capitalists and the National Institutes of Health. Entrepreneurial successThe recent surge in venture capital flowing into Denver-Boulder builds on the area's proven track record of success over the past several decades.
Persons: Tim Schoen, BioMed, Schoen, Elyse Blazevich, Kevin Koch, Koch, Edgewise, We've, Dan LaBarbera, LaBarbera, Dr Organizations: BioMed, CNBC, Blackstone, Flatiron, Enveda Biosciences, Denver, Boulder, Colorado Bioscience Association, Bioscience Association, National Institutes of Health, U.S, Pfizer, Therapeutics, University of Colorado, Edgewise Therapeutics, Research, University of Colorado's Anschutz Medical, Center, Drug, Center for Drug, for Drug, Anschutz Medical Locations: CNBC's, Denver, Boulder, Diego, Boulder , Colorado, San Diego, San Francisco, Seattle, Boston, Cambridge, Massachusetts, Aurora, Rocky, Colorado, Boulder ., Denver's
Bloomberg | Getty ImagesThe CEO of French consumer goods giant Danone downplayed the threat of obesity drugs on its food business, arguing that consumers were likely to turn to healthy products as part of their new weight loss regime. Antoine de Saint-Affrique said that surging demand for drugs like Wegovy and Mounjaro would only increase consumer appetite for more nutritional products. "We see ourselves as extremely complementary to GLP-1s," de Saint-Affrique told CNBC's Charlotte Reed Wednesday. GLP-1s, or glucagon-like peptide 1 agonists, are the underlying class of drugs in weight loss injections such as Wegovy and Mounjaro. watch nowThe rapid rise of such drugs has prompted concern among food makers, who fear falling sales as consumer appetite wanes.
Persons: Antoine de Saint, Affrique, Mounjaro, CNBC's Charlotte Reed, de, Kepler Cheuvreux Organizations: Danone SA, Bloomberg, Getty, Danone, Novo Nordisk
“Science postdocs perform the science,” Donna Ginther, an economist who studies the science labor market at the University of Kansas, told CNN. Biomedical companies take scientific contributions and, over time, aggregate them into a commercial product. Building on the discovery of mRNA in the 1960’s, the technology behind an mRNA vaccine for humans was in development for decades before the Covid-19 vaccine was first administered in 2020. By using that technology to develop their mRNA vaccines for Covid-19, pharmaceutical companies like Pfizer and Moderna made a windfall in profits. “That’s how they make money is through commercialization: they have a product, which they then patent and sell.”Why are scientists leaving academic labs?
Persons: postdocs, Donna Ginther, “ They’re, Michael Ciaglo, , , Nobel, Dr, Katalin Kariko, ” Ginther, they’re, Ginther Organizations: New, New York CNN —, National Institutes of Health, NIH, National Science Foundation, University of Kansas, CNN, , Pfizer, Moderna, Wired Magazine, NSF, World Health Organization Locations: New York, United States, Denver , Colorado, Europe, Alzheimer’s
When Oregon embarked on a landmark plan three years ago to decriminalize hard drugs, it wagered that a focus on treatment over punishment would create a new model for drug policy around the country. But after a deluge of overdose deaths and frequent chaos in the streets of Portland, Gov. Tina Kotek signed into law on Monday a measure to restore criminal penalties for drug possession. The rollback has supporters among a wide range of public officials, including Mayor Ted Wheeler of Portland, who found himself presiding over a series of crises since taking office in 2016. He has battled in court to ban daytime camping and tried to establish mass shelter locations (known in Portland as TASS sites) for those without housing.
Persons: Tina Kotek, Ted Wheeler, Wheeler Organizations: Oregon, Gov Locations: Portland
CNN —Three people were arrested in Argentina on Wednesday for threatening Argentine footballer Ángel Di María and his family, Minister of Security Patricia Bullrich said. One of the suspects, who was under investigation for drug trafficking when he was arrested, confessed that he and two accomplices had made the threats against Di María’s family. The attack happened after Di María, currently under contract with Portuguese club Benfica until June, said he would like to finish his professional career at Rosario Central, where he started his career. In 2022, the homicide rate was 22 for each 100,000 residents, according to official numbers from the government of Santa Fe province. With the support of the central government, the Santa Fe government launched “Plan Bandera” [“Plan Flag”] to fight against “narcoterrorism” at the beginning of this year.
Persons: Ángel Di María, Patricia Bullrich, Di María’s, Di María, ” Rosario, “ narcoterrorism ”, “ We’re, ” Bullrich Organizations: CNN, Portuguese, Benfica, Rosario Central, , Mayor’s, Criminal, Santa Fe, Locations: Argentina, Argentine, Rosario, Santa Fe, New York City, Santa
If the Supreme Court sides with the plaintiffs and decides to roll back or invalidate Food and Drug Administration regulations on mifepristone, it would be the first time the court undercut the federal agency’s authority. The abortion pill case before the Supreme Court could have implications far beyond abortion, potentially undermining the regulatory system for all medicines in the United States. If the Supreme Court sides with the plaintiffs and decides to roll back or invalidate F.D.A. They would have to pick up mifepristone in person from a doctor and would have to visit the doctor three times during the medication abortion process. and not to abortion providers, some medication abortion services have been stockpiling mifepristone and may continue prescribing and mailing their supply.
Persons: , Matthew J, mifepristone Organizations: Drug, Food and Drug Administration, Northern, Northern District of, Trump, U.S ., Appeals, Fifth Circuit Locations: United States, Northern District, Northern District of Texas
Last week, Nvidia announced deals with Johnson & Johnson for use of generative AI in surgery, and with GE Healthcare to improve medical imaging. "Health care, whether it's biotechnology, chemicals, or drug discovery is a very powerful area." About 41 percent of biotech CEOs surveyed by EY in late 2023 said they were looking at "concrete" ways generative AI could be used for their companies. "This is very high for my experience, having been 30 years in this industry," Ural said. It also partnered in 2021 with Schrödinger for drug discovery.
Persons: Johnson, Raj Joshi, It's, EY, it's, Colette Kress, Roche's Genentech Organizations: Nvidia, Johnson, GE Healthcare, Companies, NVIDIA, NVIDIA BioNeMo Locations: Arda, Americas, Ural, NVIDIA Clara
Police made 573 arrests in Miami Beach last spring break and confiscated over 100 guns, per The Wall Street Journal. For some drivers, spring break is their ticket to a vacation of their own, but for others, the spring break slowdown has thrown their earnings for a loop. Many, like Jared S., 27, say they don't actively seek out spring breakers, though sometimes spring break rides can be profitable. AdvertisementBreaking up with spring breakMike McGrath, 57, is glad spring break is more under control this year. AdvertisementCapitalizing on spring break crowdsRenee said maximizing her earnings during spring break comes down to knowing when to be in certain areas.
Persons: Trent T, South Florida — Uber, it's, he's, Trent, He's, I'm, You'll, Jared S, Juan, Mike McGrath, McGrath, David Lowell, he'll, Lowell, Renee, Lyft, John D, John, Hiedi, Handford, Mark, there's, Marian O, Eliezer, Edgar Organizations: Service, South Florida —, Trent, Miami Beach, Police, Street, West Palm Beach, Miami, Delray, Facebook Locations: South Florida, Miami, Miami Beach, Florida, Fort Lauderdale, Palm Beach, Cuba, West Palm, South Beach, Delray Beach, Tennessee, Ubers, Boca Raton, Nicaragua, Venezuela
Guo et al., 2024; Frontiers in Cell Developmental BiologyTo its credit, the journal quickly retracted the paper. Guo et al., 2024; Frontiers in Cell Developmental BiologyBut this rat's towering phallus is just one symptom of a crisis of fake science. Each step has holes in it that bad science could squeeze through, but the overlapping steps tend to cover each other's holes, making it difficult to squeeze all the way through the whole process. Still, bad science does make it through sometimes, and over the years more holes have opened up. The retracted paper's corresponding author, Dingjun Hao, did not respond to Business Insider's request for comment.
Persons: , Guo, Guo et, you've, Ivan Oransky, Peter Finch, Vox, Fred Fenter, Fenter, Dingjun Hao, Oransky, they've Organizations: Service, Cell Development, Business, Cell, Springer, IEEE, Guardian Locations: Swiss
CNN —Leading European soccer player Quincy Promes, who was convicted in absentia for drug smuggling last month in the Netherlands, has been arrested in Dubai at the request of Dutch prosecutors who are seeking his extradition, according to his lawyers. “The extradition procedure will now have to be completed in the United Arab Emirates,” said Promes’ Dutch lawyers in a statement on the company’s website. “We would like to point out that an independent judge in Dubai will now decide on the Dutch extradition request. “The arrested man was reportedly staying in luxury in Dubai according to various media reports. “At this time, it is not possible to provide additional information to avoid disruption of the ongoing investigation,” added Dutch prosecutors.
Persons: Quincy Promes, Promes, , , Stadio Diego Armando Maradona, Francesco Pecoraro Organizations: CNN, Ajax, Sevilla, Spartak Moscow, United Arab Emirates, Dubai Police, Reuters, Europa League, SSC Napoli, Stadio, Dubai ’ The, Dubai ’ The Amsterdam Public, Transfermarkt, Spartak Locations: Netherlands, Dubai, Brazil, Russian, Naples, Italy, Europe, Dubai ’, Dubai ’ The Amsterdam, Moscow, Amsterdam, UAE
Injection pens of Novo Nordisk's weight-loss drug Wegovy are shown in this photo illustration in Oslo, Norway, Nov. 21, 2023. The approval also demonstrates that weight loss drugs have significant health benefits beyond shedding unwanted pounds and regulating blood sugar. The FDA said Wegovy patients should use Wegovy in addition to a reduced calorie diet and increased physical activity. Novo Nordisk expects to receive a similar Wegovy approval in the EU this year. The study tested Wegovy in roughly 17,500 people with obesity and heart disease but who did not have diabetes.
Persons: John Sharretts, Ozempic, Wegovy, Eli Lilly, Zepbound Organizations: Drug Administration, Novo Nordisk, Diabetes, FDA's Center, Drug, Research, FDA, Nordisk Locations: Oslo, Norway, Danish, U.S
Has San Francisco Lost Its Liberal Soul?
  + stars: | 2024-03-08 | by ( Heather Knight | ) www.nytimes.com   time to read: +1 min
Have San Francisco voters lost the bleeding hearts they have been known for — or are they just frustrated? City voters resoundingly passed two ballot measures this week that probably wouldn’t have seen the light of day a few years ago. Critics of the measures said that residents had veered to the right and that billionaires had bought the city by throwing money at campaigns for the measures. But Mayor London Breed, who faces a tough race for re-election in November and who placed the two measures on the ballot, brushed off claims that the city had lost its liberal soul. In her annual State of the City address on Thursday, Breed argued that it was progressive to invest in public safety to protect vulnerable older residents and immigrants, and to push for drug treatment for those who need it.
Persons: resoundingly, London Breed, Breed Organizations: San Francisco, City, London
CNN —Former President of Honduras Juan Orlando Hernández was found guilty Friday of drug trafficking by an American jury after a two-week trial in Manhattan federal court. Prosecutors had accused Hernández, 55, of conspiring with drug cartels during his tenure as they moved more than 400 tons of cocaine through Honduras toward the United States. In exchange, prosecutors said, Hernández received millions of dollars in bribes that he used to fuel his rise in Honduran politics. Hernández was president of Honduras from 2014 until 2022. He was extradited to the United States in 2022 after the completion of his second term in office on charges of conspiracy to import cocaine into the United States, conspiracy to possess firearms and destructive devices for drug trafficking, and possession of this type of weapon during the drug trafficking conspiracy.
Persons: Honduras Juan Orlando Hernández, Prosecutors, Hernández, ” Prosecutors, “ He’s, ” Raymond Colon, , , Hernandez “, General Merrick Garland, Hernández “ Organizations: CNN, Justice Department, , Honduran National Police Locations: Honduras, Manhattan, United States
The situation was so dire last year at one Walgreens store in San Francisco, employees resorted to padlocking frozen foods. The effort to undo some aspects of Prop 47 comes amid a broader check on some other liberal crime enforcement policies in America. Police data shows that larceny theft, which includes retail theft and car break-ins, is down 37% from this time last year. On Tuesday, San Francisco voters approved two ballot measures spearheaded by Breed. Last September, the state announced it would be sending $267 million to law enforcement agencies throughout the state to tackle organized retail theft.
Persons: Gavin Newsom, It’s, , Jason Henry, , Marlene Harden’s, Harden, Chloe, , ” Harden, Marlene Harden's, Thanh Tran, Tran, Ella Baker, CNN Lenore Anderson, ” Anderson, Richard Bailey of Coronado, Breed, Tayfun, , Miracle, don’t, We’re, Newsom, He’s Organizations: San Francisco CNN —, Republican, Democratic, Democratic Gov, CNN, Public, Institute of California, state’s Department of Justice, Walgreens, Walmart, ” Walmart, Westfield San Francisco Centre, New York Times, “ Walgreens, , National Retail Federation, Target, Ella Baker Center for Human, Attorneys, San Francisco Mayor London, San Francisco Mayor London Breed, Anadolu Agency, San Francisco Chronicle, Police, , San Francisco, Breed Locations: San, California, San Francisco, America, Oregon’s, San Diego County, Francisco, Texas, South Carolina
The problem: Conventional scorekeeping for chip companies may miss the scale of Nvidia's opportunity ahead. NVDA 1Y mountain Nvidia's stock performance over the past 12 months. "Health care will be the largest technology industry in the coming years," Powell predicted at the TD Cowen conference. However, Powell said Nvidia's previous work on autonomous driving help the company's push into new corners of that market. As a subscriber to the CNBC Investing Club with Jim Cramer, you will receive a trade alert before Jim makes a trade.
Persons: Morgan Stanley's, Colette Kress, Kress, Kimberly Powell, Powell, Cowen, haven't, Nvidia's, it's, Jim Cramer's, Jim Cramer, Jim, Justin Sullivan Organizations: Nvidia, Management, CNBC Locations: U.S
Miami Beach has launched an ad campaign "breaking up" with spring break tourism. Last year, two people were fatally shot during spring break, leading Miami Beach to declare a state of emergency. Police made 573 arrests in Miami Beach last spring break, as well as confiscated over 100 guns, The Wall Street Journal reported. Though many travelers have already made plans — and may not have seen the ad campaign — the "breakup" could reduce disorder. Still, some commenters on YouTube and X noted that these restrictions may not stop spring break travelers from coming.
Persons: , it's, Dan Gelber, Miami Beach Mayor Steven Meiner Organizations: Miami Beach, Service, YouTube, Police, Street Journal, Miami Beach's, Beach, Miami Beach Mayor Locations: Florida, Miami, Miami Beach
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